Person | Mechanoresponsive Materials | Adolphe Merkle Institute

BAROSOVA Hana

Alumni

BioNanomaterials

Adolphe Merkle Institute Chemin des Verdiers 4 CH-1700 Fribourg Switzerland

Office:	C246
Phone:	+41 26 300 9522
Email:	hana.barosova@unifr.ch

Projects team

3D Tissue Models to Assess Hazards (Lung / Intestine / Skin)

Tissue-based 3D cell culture models mimic physiological and barrier properties of human skin, lung or…

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Hazard Assessment of Aerosolized Nanomaterials

Aerosolisation approaches for a direct and controlled exposure of nanomaterials on the cell surface

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Theses

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3D human co-cultures for predicting nanomaterial possible adverse effects on human health with a focus on multi-walled carbon nanotubes, 2019
Publications

Human Asthmatic Bronchial Cells Are More Susceptible to Subchronic Repeated Exposures of Aerosolized Carbon Nanotubes At Occupationally Relevant Doses Than Healthy Cells
Chortarea Savvina, Barosova Hana, Clift Martin James David, Wick Peter, Petri-Fink Alke, Rothen-Rutishauser Barbara
ACS Nano (2017)

Characteristics and properties of nano-LiCoO2 synthesized by pre-organized single source precursors: Li-ion diffusivity, electrochemistry and biological assessment
Brog Jean-Pierre, Crochet Aurélien, Seydoux Joël, Clift Martin J. D., Baichette Benoît, Maharajan Sivarajakumar, Barosova Hana, Brodard Pierre, Spodaryk Mariana, Züttel Andreas, Rothen-Rutishauser Barbara, Kwon Nam Hee, Fromm Katharina M.
Journal of Nanobiotechnology (2017)

Carbon nanodots: Opportunities and limitations to study their biodistribution at the human lung epithelial tissue barrier
Durantie Estelle, Barosova Hana, Drasler Barbara, Rodriguez-Lorenzo Laura, Urban Dominic A., Vanhecke Dimitri, Septiadi Dedy, Hirschi-Ackermann Liliane, Petri-Fink Alke, Rothen-Rutishauser Barbara
Biointerphases (2018)

Single exposure to aerosolized graphene oxide and graphene nanoplatelets did not initiate an acute biological response in a 3D human lung model
Drasler Barbara, Kucki Melanie, Delhaes Flavien, Buerki-Thurnherr Tina, Vanhecke Dimitri, Korejwo Daria, Chortarea Savvina, Barosova Hana, Hirsch Cordula, Petri-Fink Alke, Rothen-Rutishauser Barbara, Wick Peter
Carbon (2018)

Biological response of an in vitro human 3D lung cell model exposed to brake wear debris varies based on brake pad formulation
Barosova Hana, Chortarea Savvina, Peikertova Pavlina, Clift Martin J. D., Petri-Fink Alke, Kukutschova Jana, Rothen-Rutishauser Barbara
Archives of Toxicology (2018)

Leveraging proteomics to compare submerged versus air-liquid interface carbon nanotube exposure to a 3D lung cell model
Hilton G., Barosova H., Petri-Fink A., Rothen-Rutishauser B., Bereman M.
Toxicology in Vitro (2019)

Profibrotic Activity of Multiwalled Carbon Nanotubes Upon Prolonged Exposures in Different Human Lung Cell Types
Chortarea Savvina, Zerimariam Fikad, Barosova Hana, Septiadi Dedy, Clift Martin J.D., Petri-Fink Alke, Rothen-Rutishauser Barbara
Applied In Vitro Toxicology (2018)

Quantification of Carbon Nanotube Doses in Adherent Cell Culture Assays Using UV-VIS-NIR Spectroscopy
Septiadi Dedy, Rodriguez-Lorenzo Laura, Balog Sandor, Spuch-Calvar Miguel, Spiaggia Giovanni, Taladriz-Blanco Patricia, Barosova Hana, Chortarea Savvina, Clift Martin J. D., Teeguarden Justin, Sharma Monita, Petri-Fink Alke, Rothen-Rutishauser Barbara
Nanomaterials (2019)

Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes
Barosova Hana, Maione Anna G., Septiadi Dedy, Sharma Monita, Haeni Laetitia, Balog Sandor, O’Connell Olivia, Jackson George R., Brown David, Clippinger Amy J., Hayden Patrick, Petri-Fink Alke, Stone Vicki, Rothen-Rutishauser Barbara
ACS Nano (2020)

Multicellular Human Alveolar Model Composed of Epithelial Cells and Primary Immune Cells for Hazard Assessment
Barosova Hana, Drasler Barbara, Petri-Fink Alke, Rothen-Rutishauser Barbara
Journal of Visualized Experiments (2020)

Combined exposure of diesel exhaust particles and respirable Soufrière Hills volcanic ash causes a (pro-)inflammatory response in an in vitro multicellular epithelial tissue barrier model
Tomašek Ines, Horwell Claire J., Damby David E., Barošová Hana, Geers Christoph, Petri-Fink Alke, Rothen-Rutishauser Barbara, Clift Martin J. D.
Particle and Fibre Toxicology (2016)

Innovative preclinical models for pulmonary drug delivery research
Ehrmann Stephan, Schmid Otmar, Darquenne Chantal, Rothen-Rutishauser Barbara, Sznitman Josue, Yang Lin, Barosova Hana, Vecellio Laurent, Mitchell Jolyon, Heuze-Vourc’h Nathalie
Expert Opinion on Drug Delivery (2020)

Characteristics and properties of nano-LiCoO2 synthesized by pre-organized single source precursors: Li-ion diffusivity, electrochemistry and biological assessment
Brog Jean-Pierre, Crochet Aurélien, Seydoux Joël, Clift Martin J. D., Baichette Benoît, Maharajan Sivarajakumar, Barosova Hana, Brodard Pierre, Spodaryk Mariana, Züttel Andreas, Rothen-Rutishauser Barbara, Kwon Nam Hee, Fromm Katharina M.
Journal of Nanobiotechnology (2017)

Human Asthmatic Bronchial Cells Are More Susceptible to Subchronic Repeated Exposures of Aerosolized Carbon Nanotubes At Occupationally Relevant Doses Than Healthy Cells
Chortarea Savvina, Barosova Hana, Clift Martin James David, Wick Peter, Petri-Fink Alke, Rothen-Rutishauser Barbara
ACS Nano (2017)

A comparison of suspension versus air–liquid interface experiments to assess the (pro-)fibrotic potential of carbon nanotubes in vitro
Barosova Hana, Chortarea Savvina, Septiadi Dedy, Sharma Monita, Clippinger Amy J., Zerimariam Fikad, Petri-Fink Alke, Rothen-Rutishauser Barbara
Toxicology Letters (2017)

An In Vitro Lung System to Assess the Proinflammatory Hazard of Carbon Nanotube Aerosols
Barosova Hana, Karakocak Bedia Begum, Septiadi Dedy, Petri-Fink Alke, Stone Vicki, Rothen-Rutishauser Barbara
International Journal of Molecular Sciences (2020)

Rapid and sensitive quantification of cell-associated multi-walled carbon nanotubes
Steinmetz Lukas, Bourquin Joel, Barosova Hana, Haeni Laetitia, Caldwell Jessica, Milosevic Ana, Geers Christoph, Bonmarin Mathias, Taladriz-Blanco Patricia, Rothen-Rutishauser Barbara, Petri-Fink Alke
Nanoscale (2020)

An Inflamed Human Alveolar Model for Testing the Efficiency of Anti-inflammatory Drugs in vitro
Drasler Barbara, Karakocak Bedia Begum, Tankus Esma Bahar, Barosova Hana, Abe Jun, Sousa de Almeida Mauro, Petri-Fink Alke, Rothen-Rutishauser Barbara
Frontiers in Bioengineering and Biotechnology (2020)

Correction to Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes
Barosova Hana, Maione Anna G., Septiadi Dedy, Sharma Monita, Haeni Laetitia, Balog Sandor, O’Connell Olivia, Jackson George R., Brown David, Clippinger Amy J., Hayden Patrick, Petri-Fink Alke, Stone Vicki, Rothen-Rutishauser Barbara
ACS Nano (2020)

Inter-laboratory variability of A549 epithelial cells grown under submerged and air-liquid interface conditions
Barosova Hana, Meldrum Kirsty, Karakocak Bedia Begum, Balog Sandor, Doak Shareen H., Petri-Fink Alke, Clift Martin J.D., Rothen-Rutishauser Barbara
Toxicology in Vitro (2021)

Comparing species-different responses in pulmonary fibrosis research: Current understanding of in vitro lung cell models and nanomaterials
Keshavan Sandeep, Bannuscher Anne, Drasler Barbara, Barosova Hana, Petri-Fink Alke, Rothen-Rutishauser Barbara
European Journal of Pharmaceutical Sciences (2023)

BAROSOVA Hana

3D Tissue Models to Assess Hazards (Lung / Intestine / Skin)

Hazard Assessment of Aerosolized Nanomaterials