Person | Mechanoresponsive Materials | Adolphe Merkle Institute

LEHNER Roman

Alumni

Postdoctoral researcher, BioNanomaterials

Adolphe Merkle Institute Chemin des Verdiers 4 CH-1700 Fribourg Switzerland

Office:	B220
Phone:	+41 26 300 9428
Email:	roman.lehner@unifr.ch
	0000-0002-0478-5445

Projects team

Plastic Micro- and Nanoparticles

Preparation and characterization of micro- and nano-sized plastic particles for human hazard assessments.

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3D Tissue Models to Assess Hazards (Lung / Intestine / Skin)

Tissue-based 3D cell culture models mimic physiological and barrier properties of human skin, lung or…

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Plastic Micro- and Nanoparticles in Analytically Complex Environments

Develop standardized methods for the detection of plastic micro- and nanoparticles

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Publications

Preparation of Well-Defined Fluorescent Nanoplastic Particles by Confined Impinging Jet Mixing
Livius F. Muff, Sandor Balog, Jozef Adamcik, Christoph Weder, Roman Lehner
Environmental Science & Technology (2023)

The micro-, submicron-, and nanoplastic hunt: A review of detection methods for plastic particles
Jessica Caldwell, Patricia Taladriz-Blanco, Roman Lehner, Andriy Lubskyy, Roberto Diego Ortuso, Barbara Rothen-Rutishauser, Alke Petri-Fink
Chemosphere 293 , 133514 (2022)

Understanding the Development, Standardization, and Validation Process of Alternative In Vitro Test Methods for Regulatory Approval from a Researcher Perspective
Aurora Bas, Nicole Burns, Andrew Gulotta, James Junker, Barbara Drasler, Roman Lehner, Lothar Aicher, Samuel Constant, Alke Petri‐Fink, Barbara Rothen‐Rutishauser
Small (2021)

Fluorescent plastic nanoparticles to track their interaction and fate in physiological environments
Jessica Caldwell, Roman Lehner, Sandor Balog, Christian Rhême, Xin Gao, Dedy Septiadi, Christoph Weder, Alke Petri-Fink, Barbara Rothen-Rutishauser
Environmental Science: Nano (2021)

Spatial and temporal analysis of meso- and microplastic pollution in the Ligurian and Tyrrhenian Seas
Jessica Caldwell, Livius F. Muff, Christopher K. Pham, Alke Petri-Fink, Barbara Rothen-Rutishauser, Roman Lehner
Marine Pollution Bulletin (2020)

A novel 3D intestine barrier model to study the immune response upon exposure to microplastics.
Roman Lehner, Wendel Wohlleben, Dedy Septiadi, Robert Landsiedel, Alke Petri-Fink, Barbara Rothen-Rutishauser
Archives of toxicology (2020)

Assessing meso- and microplastic pollution in the Ligurian and Tyrrhenian Seas

Marine Pollution Bulletin (2019)

Emergence of Nanoplastic in the Environment and Possible Impact on Human Health
Roman Lehner, Christoph Weder, Alke Petri-Fink, Barbara Rothen-Rutishauser
Environmental Science & Technology (2019)

Subcellular Imaging of Liquid Silicone Coated-Intestinal Epithelial Cells
Peter Nirmalraj, Roman Lehner, Damien Thompson, Barbara Rothen-Rutishauser, Michael Mayer
Scientific Reports (2018)

Biodistribution, Clearance, and Long-Term Fate of Clinically Relevant Nanomaterials.
Joël Bourquin, Ana Milosevic, Daniel Hauser, Roman Lehner, Fabian Blank, Alke Petri‐Fink, Barbara Rothen‐Rutishauser
Advanced materials (Deerfield Beach, Fla.) (2018)

Efficient Receptor Mediated siRNA Delivery in Vitro by Folic Acid Targeted Pentablock Copolymer-Based Micelleplexes.
Roman Lehner, Kegang Liu, Xueya Wang, Patrick Hunziker
Biomacromolecules (2017)

A comparison of plasmid DNA delivery efficiency and cytotoxicity of two cationic diblock polyoxazoline copolymers
Roman Lehner, Kegang Liu, Xueya Wang, Marc Wolf, Patrick Hunziker
Nanotechnology (2017)

Nanoplastic Impact on Human Health—A 3D Intestinal Model to Study the Interaction with Nanoplastic Particles
Roman Lehner, Alke Petri-Fink, Barbara Rothen-Rutishauser
Proceedings of the International Conference on Microplastic Pollution in the Mediterranean Sea (2017)

Plasmid linearization changes shape and efficiency of transfection complexes
Roman Lehner, Xueya Wang, Patrick Hunziker
nano Online (2016)

Why not just switch on the light?: light and its versatile applications in the field of nanomedicine
Roman Lehner, Patrick Hunziker
nano Online (2016)

Structure of the oligogalacturonate-specific KdgM porin.
C. A. J. Hutter, R. Lehner, Ch. Wirth, G. Condemine, C. Peneff, T. Schirmer
Acta crystallographica. Section D, Biological crystallography (2014)

Intelligent nanomaterials for medicine: Carrier platforms and targeting strategies in the context of clinical application
Roman Lehner, Xueya Wang, Stephan Marsch, Patrick Hunziker
Nanomedicine: Nanotechnology, Biology and Medicine (2013)

Histomorphometric, CT Arthrographic, and Biomechanical Mapping of the Human Ankle
Olaf Buettner, André Leumann, Roman Lehner, Salome Dell-Kuster, Rachel Rosenthal, Magdalena Mueller-Gerbl, Victor Valderrabano
Foot & Ankle International (2013)

Polydimethylsiloxane embedded mouse aortaex vivoperfusion model: proof-of-concept study focusing on atherosclerosis
Xueya Wang, Marc P. Wolf, Rahel Bänziger Keel, Roman Lehner, Patrick R. Hunziker
Journal of Biomedical Optics (2012)

Designing switchable nanosystems for medical application
Roman Lehner, Xueya Wang, Marc Wolf, Patrick Hunziker
Journal of Controlled Release (2012)

LEHNER Roman

Plastic Micro- and Nanoparticles

3D Tissue Models to Assess Hazards (Lung / Intestine / Skin)

Plastic Micro- and Nanoparticles in Analytically Complex Environments