Person | Mechanoresponsive Materials | Adolphe Merkle Institute

CHORTAREA Savvina

Alumni

PhD student, BioNanomaterials

Projects team

Hazard Assessment of Aerosolized Nanomaterials

Aerosolisation approaches for a direct and controlled exposure of nanomaterials on the cell surface

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Theses

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Realistic exposure scenarios to study nanoparticle-lung cell interactions, 2017
Publications

Air–Liquid Interface In Vitro Models for Respiratory Toxicology Research: Consensus Workshop and Recommendations
Lacroix Ghislaine, Koch Wolfgang, Ritter Detlef, Gutleb Arno C., Larsen Søren Thor, Loret Thomas, Zanetti Filippo, Constant Samuel, Chortarea Savvina, Rothen-Rutishauser Barbara, Hiemstra Pieter S., Frejafon Emeric, Hubert Philippe, Gribaldo Laura, Kearns Peter, Aublant Jean-Marc, Diabaté Silvia, Weiss Carsten, de Groot Antoinette, Kooter Ingeborg
Applied In Vitro Toxicology (2018)

Single exposure to aerosolized graphene oxide and graphene nanoplatelets did not initiate an acute biological response in a 3D human lung model
Drasler Barbara, Kucki Melanie, Delhaes Flavien, Buerki-Thurnherr Tina, Vanhecke Dimitri, Korejwo Daria, Chortarea Savvina, Barosova Hana, Hirsch Cordula, Petri-Fink Alke, Rothen-Rutishauser Barbara, Wick Peter
Carbon (2018)

Biological response of an in vitro human 3D lung cell model exposed to brake wear debris varies based on brake pad formulation
Barosova Hana, Chortarea Savvina, Peikertova Pavlina, Clift Martin J. D., Petri-Fink Alke, Kukutschova Jana, Rothen-Rutishauser Barbara
Archives of Toxicology (2018)

Profibrotic Activity of Multiwalled Carbon Nanotubes Upon Prolonged Exposures in Different Human Lung Cell Types
Chortarea Savvina, Zerimariam Fikad, Barosova Hana, Septiadi Dedy, Clift Martin J.D., Petri-Fink Alke, Rothen-Rutishauser Barbara
Applied In Vitro Toxicology (2018)

Acute effects of multi-walled carbon nanotubes on primary bronchial epithelial cells from COPD patients
Beyeler Seraina, Chortarea Savvina, Rothen-Rutishauser Barbara, Petri-Fink Alke, Wick Peter, Tschanz Stefan A., von Garnier Christophe, Blank Fabian
Nanotoxicology (2018)

Distribution of polymer-coated gold nanoparticles in a 3D lung model and indication of apoptosis after repeated exposure
Chortarea Savvina, Fytianos Kleanthis, Rodriguez-Lorenzo Laura, Petri-Fink Alke, Rothen-Rutishauser Barbara
Nanomedicine (2018)

Quantification of Carbon Nanotube Doses in Adherent Cell Culture Assays Using UV-VIS-NIR Spectroscopy
Septiadi Dedy, Rodriguez-Lorenzo Laura, Balog Sandor, Spuch-Calvar Miguel, Spiaggia Giovanni, Taladriz-Blanco Patricia, Barosova Hana, Chortarea Savvina, Clift Martin J. D., Teeguarden Justin, Sharma Monita, Petri-Fink Alke, Rothen-Rutishauser Barbara
Nanomaterials (2019)

Release of graphene-related materials from epoxy-based composites: characterization, quantification and hazard assessment in vitro
Netkueakul Woranan, Korejwo Daria, Hammer Tobias, Chortarea Savvina, Rupper Patrick, Braun Oliver, Calame Michel, Rothen-Rutishauser Barbara, Buerki-Thurnherr Tina, Wick Peter, Wang Jing
Nanoscale (2020)

Human Asthmatic Bronchial Cells Are More Susceptible to Subchronic Repeated Exposures of Aerosolized Carbon Nanotubes At Occupationally Relevant Doses Than Healthy Cells
Chortarea Savvina, Barosova Hana, Clift Martin James David, Wick Peter, Petri-Fink Alke, Rothen-Rutishauser Barbara
ACS Nano (2017)

A comparison of suspension versus air–liquid interface experiments to assess the (pro-)fibrotic potential of carbon nanotubes in vitro
Barosova Hana, Chortarea Savvina, Septiadi Dedy, Sharma Monita, Clippinger Amy J., Zerimariam Fikad, Petri-Fink Alke, Rothen-Rutishauser Barbara
Toxicology Letters (2017)

Gene expression profiling of human macrophages after graphene oxide and graphene nanoplatelets treatment reveals particle-specific regulation of pathways
Korejwo Daria, Chortarea Savvina, Louka Chrysovalanto, Buljan Marija, Rothen-Rutishauser Barbara, Wick Peter, Buerki-Thurnherr Tina
NanoImpact (2023)

Hazard assessment of abraded thermoplastic composites reinforced with reduced graphene oxide
Chortarea Savvina, Kuru Ogul Can, Netkueakul Woranan, Pelin Marco, Keshavan Sandeep, Song Zhengmei, Ma Baojin, Gómes Julio, Abalos Elvira Villaro, Luna Luis Augusto Visani de, Loret Thomas, Fordham Alexander, Drummond Matthew, Kontis Nikolaos, Anagnostopoulos George, Paterakis George, Cataldi Pietro, Tubaro Aurelia, Galiotis Costas, Kinloch Ian, Fadeel Bengt, Bussy Cyrill, Kostarelos Kostas, Buerki-Thurnherr Tina, Prato Maurizio, Bianco Alberto, Wick Peter
Journal of Hazardous Materials (2022)