The physicochemical properties of nanoparticles and exposure methodology significantly influence cellular assays, with responses being dose-dependent and requiring accurate dosing and metrics. Nanoparticle dosimetry and computational particle kinetic models are vital for in vitro toxicology studies. Our objective is to develop and apply particle kinetic concepts across diverse particle systems, including nanoparticles from industrial and academic sources, through the integration of mathematical modeling, advanced instrumentation, and experimental approaches. 

Selected publications: 

The Influence of Liquid Menisci on Nanoparticle Dosimetry in Submerged Cells - Glaubitz - 2023 - Small - Wiley Online Library 

Particokinetics and in vitro dose of high aspect ratio nanoparticles - Nanoscale (RSC Publishing) 

Factors Affecting Nanoparticle Dose–Exposure and Cell Response | SpringerLink 

Nanoparticle administration method in cell culture alters particle-cell interaction | Scientific Reports 

Nanoparticle Polydispersity Can Strongly Affect In Vitro Dose - Rodriguez‐Lorenzo - 2015 - Particle & Particle Systems Characterization - Wiley Online Library 

In vitro dosimetry of agglomerates - Nanoscale (RSC Publishing)