Combustion-derived particles from transportation are known to contribute to adverse human health effects. Fractions of these particles deposit within the respiratory tract upon inhalation and induce adverse effects. Ultrafine particles (UFPs) can even translocate from the alveoli across the air-blood tissue barrier into the bloodstream, accumulating in secondary organs beyond the lungs, such as the brain, liver, kidneys, and intestines. Understanding the impacts of UFPs on secondary organs remains an area of active investigation. In this study, we aim to evaluate the effects of combustion-derived particles such as diesel exhaust particles (DEPs) and UFPs on human intestine tissue in vitro.  

Funding source:

• ULTRHAs from the European Union’s Horizon 2020 research and innovative program under grant agreement No 955390 

• https://www.fhi.no/en/studies/ultrhas/  

• https://cordis.europa.eu/project/id/955390