Macromolecular Chemistry Research Group

The research carried out by AMI's Macromolecular Chemistry Group, led by Professor Nico Bruns, is motivated by a fascination for polymers and proteins. The rationale behind our work exploits the various functions of proteins, such as their ability to self-assemble into well-defined three dimensional structures and to act as catalysts, and merges them with polymer systems, which are relatively easy to synthesise and can be tailored to specific applications. Via this approach, some of the best aspects of two different domains of macromolecular chemistry are combined in order to exploit the catalytic power of enzymes, to create novel nanosystems and to develop materials with unprecendented new functions. Three lines of research illustrate our strategy:

1) Enzyme-catalyzed controlled/living radical polymerization (ATRPases)

2) Protein cages and polymersomes as nanoreactors

3) Polymer-protein hybrid materials with the capability to self-report damage

Adolphe Merkle Institute - Chemin des Verdiers 4 - CH-1700 Fribourg - Phone +41 26 300 9254